ࡱ>  _ bjbj h1bh1b9~F  8-r:L>2NR-T-T-T-T-T-T-$/2Bx-9#@"##x--)')')'#v8V8R-)'#R-)')')>) dme$)>--0-),3G%B3)3)D^d)' !c^^^x-x-&^^^-####3^^^^^^^^^ B :  SUPPLEMENTAL CONSENT FOR COLLECTION, STORAGE AND USE OF BIOLOGICAL SAMPLES FOR FUTURE RESEARCH, INCLUDING GENETIC RESEARCH and AUTHORIZATION FOR USE AND DISCLOSURE OF PROTECTED HEALTH INFORMATION Principal Investigator:  FORMTEXT       , [M.D., Ph.D., etc.] Other Staff (identified by role):  FORMTEXT       , [M.D., Ph.D., etc.] Contact Phone number(s): (419)  FORMTEXT       This consent and authorization is for a research study that is separate from the main study. The purpose of the main study is {provide a short description of the main study, e.g. to determine the safety and efficacy of the drug (insert drug name) in patients with your diagnosis of {insert diagnosis(es)}. You are invited to participate in this separate genetic research study. You do not have to participate in this study to be eligible for the main study. Explanation of Genetic Research Scientists are currently studying what role genes (DNA) play in health and disease. DNA is passed from parent to child, and helps to determine traits like eye color. DNA also determines traits such as the ability to fight or cause certain diseases. The goal of studying genes is to one day find better ways to prevent and treat disease. Biological samples, such as blood, contain a persons genes. Researchers study biological samples from large groups of people to learn how genes affect health. Some of these people all have the same disease, and some do not have the disease. Studying both groups helps us find out more about the effect of common genetic traits on the risk for various diseases. Purpose of This Research The purpose of this second research study is to {explain why study is being done in one to three sentences. The purpose may be to discover genes, find out how genes work, or learn how to use what we know about genes to treat or prevent disease. The explanation must describe the specific purpose of this study as it relates to genetics, e.g., to find out whether there are differences in the way that different people respond to drugs based on their individual genes, which are found in their DNA.}. Description of The Research Procedures and Duration of Your Involvement If you agree to participate in this second study, a sample of {state amount and type of sample, e.g. approximately 2 teaspoons of your blood} will be taken from {state where sample will be taken from, e.g. your arm} and donated to The University of Toledo Medical Center for research purposes. This sample will be taken in addition to any samples required for the main study or your regular care. We will store your donated sample to use for this second study. We expect that your participation should take no more than ________ {fill in estimated time}. In addition to using this sample for this second study, we will also ask for your permission to store and use this sample in future studies that have not yet been planned. If you consent to the future use of your sample, any such research will be approved by an institutional review board (IRB) before the research is done. An IRB is an independent committee that consists of scientists, non-scientists and members of the community who ensure that the research is ethical and that the rights of participants are protected. If such future research is done, the investigators using your donated sample will not receive any additional information that could identify you (like your name, medical record number, or social security number). You can change your mind about permitting the use of your sample at any time. Some of your sample may be used for genetic testing. However, the results will not be told to you, unless you request, and will not be placed into your medical record. Your sample will only be used for research and will not be sold. {Note, if the finished consent form is an odd number of pages, please insert another page as page two, and type NO TEXT THIS PAGE on the otherwise blank page. The final consent form must be an even number of pages.} Risks and Discomforts You May Experience If You Take Part In This Research Risks associated with {fill in procedure, e.g., drawing blood from your arm} include {state risks of procedure, e.g. momentary discomfort and/or bruising. Infection, excess bleeding, clotting, or fainting are also possible, although unlikely.}. The greatest risk associated with the storage of your samples is a possible loss of confidential information that you may not want disclosed. However, your sample will be identified only by a code and procedures are in place to keep these codes private. Investigators using the stored samples in the future will not have access to the codes. Possible Benefit To You Or To Others For Taking Part In This Research We do not expect that you will receive any benefit from this study. The goal of this study is to one day find better ways to prevent and treat {insert targeted disease or condition(s)}. By taking part in this research, you will contribute to progress in science and medicine. Other people may benefit in the future from the information we learn by studying your samples. Payment Or Other Compensation To The Research Site The University of Toledo Medical Center {state is or is not} receiving money or other benefits {include this phrase for sponsored studies: from the sponsor of this research} as reimbursement for expenses related to conducting the research. Payment Or Other Compensation To You For Taking Part In This Research You will not be paid for donating your sample or taking part in this research. {If the subject will receive any compensation for their participation, describe the amount or nature. Compensation includes money, free items or reimbursed transportation. Money may be offered to reimburse expenses, time, inconvenience and transportation. However, money may not be used as an inducement to assume risks.} Voluntary Participation Taking part in this study is voluntary. You may refuse to participate or discontinue participation at any time without a penalty or a loss of benefits to which you are otherwise entitled. You may refuse to participate in this second research study and still participate in the main research study. If you decide not to participate or to discontinue participation, your decision will not affect your future relations with the University of Toledo or The University of Toledo Medical Center. If you decide to withdraw from this study prior to its completion, you may require us to destroy your genetic material by giving notice in writing to [list the name and address of the research study personnel that should receive the notice]. Please indicate your preference for use of your donated sample in future, unplanned studies by circling the a, the b or the c for each of the four (4) statements below. [Instructions (to be deleted before use of form) for study personnel completing this template: delete choice c if there is no current research planned, i.e. consent is for future, unplanned research] Samples of my biological material: May be stored with links to my identity (confidential codes), and then used for future research. May be stored if all links to my identity are destroyed, and then used for future research. Must be destroyed after the completion of the research described in this form. If I have given permission for my biological material to be kept by The University of Toledo, it may be used for future studies: By the UTMC Principal Investigator listed on page one of this form, or by other investigators. Only by the UTMC Principal Investigator listed on page one of this form. My genetic material may not be used for future studies. If my biological material is kept, it may be used: For studies of any condition or disease. Only for studies related to {insert conditions/diseases in this study}. My genetic material may not be kept for future studies. If biological information is obtained pertaining to my health and my study doctor believes it would alter my care: Please contact me about information pertaining to my health. Do not contact me. Confidentiality And Use And Disclosure Of Your Protected Health Information By agreeing to take part in this research study, you give to The University of Toledo (UT), the Principal Investigator and all personnel associated with this research study your permission to use or disclose health information that can be identified with you that we obtain in connection with this study. We will use this information for the purpose of conducting the research study as described in this form. The information that we will use or disclose includes {describe the information or nature of information in a specific and meaningful manner, including the source or location of the information}. We may use this information ourselves, or we may disclose or provide access to the information to {state the name or other specific identification of the persons, class of persons, or agencies that could receive the information and the purpose of the use or disclosure (e.g. Food and Drug Administration or other applicable governmental agencies (for the purpose of safety, efficacy and compliance reports), study sponsor and its designees (for study oversight and monitoring), coordinating center (for data collection and study monitoring), outside laboratories (for processing of specimens), other sites participating in this research (for multi-institutional studies), statistician (for analysis of data), etc.} as part of the research study. Under some circumstances, the Institutional Review Board and Research and Sponsored Programs of the University of Toledo may review your information for compliance audits. We may also disclose your protected health information when required by law, such as in response to judicial orders. The University of Toledo is required by law to protect the privacy of your health information, and to use or disclose the information we obtain about you in connection with this research study only as authorized by you in this form. There is a possibility that the information we disclose may be re-disclosed by the persons we give it to, and no longer protected. However, we will encourage any person who receives your information from us to continue to protect and not re-disclose the information. Your permission for us to use or disclose your protected health information as described in this section is voluntary. However, you will not be allowed to participate in the research study unless you give us your permission to use or disclose your protected health information by signing this document. You have the right to revoke (cancel) the permission you have given to us to use or disclose your protected health information at any time by giving written notice to {list the name and address of the research study personnel that should receive the revocation}. However, a cancellation will not apply if we have acted with your permission, for example, information that already has been used or disclosed prior to the cancellation. Also, a cancellation will not prevent us from continuing to use and disclose information that was obtained prior to the cancellation as necessary to maintain the integrity of the research study. Except as noted in the above paragraph, your permission for us to use and disclose your protected health information has no expiration date. A more complete statement of UTs Privacy Practices is set forth in its Joint Notice of Privacy Practices. If you have not already received this Notice, a member of the research team will provide this to you. If you have any further questions concerning privacy, you may contact the University of Toledos Privacy Officer at 419-383-3413. Note: All of the information in the following table (from "Offer to Answer Questions" to the end of the document) is an integral part of the consent form and cannot be divided between two pages. Please remember to insert an additional page in this document (as the 2nd single sided page) with "NO TEXT THIS PAGE" typed on it when appropriate (see instructions on top of first page) if this document has an odd number of single-sided pages. If there is a large gap in text between "Offer to Answer Section" and the section prior to it, please type "CONTINUED NEXT PAGE" in the gap. OFFER TO ANSWER QUESTIONS Before you sign this form, please ask any questions on any aspect of this study that is unclear to you. You may take as much time as necessary to think it over. If you have questions regarding the research at any time before, during or after the study, you may contact{insert name of one or more researchers and their telephonenumber(s)}. If you have questions beyond those answered by the research team or your rights as a research subject or research-related injuries, please feel free to contact the Chairperson of the University of Toledo Biomedical Institutional Review Board at 419-383-6796.SIGNATURE SECTION (Please read carefully) YOU ARE MAKING A DECISION WHETHER OR NOT TO PARTICIPATE IN THIS RESEARCH STUDY. YOUR SIGNATURE INDICATES THAT YOU HAVE READ THE INFORMATION PROVIDED ABOVE, YOU HAVE HAD ALL YOUR QUESTIONS ANSWERED, AND YOU HAVE DECIDED TO TAKE PART IN THIS RESEARCH.BY SIGNING THIS DOCUMENT YOU AUTHORIZE US TO USE OR DISCLOSE YOUR PROTECTED HEALTH INFORMATION AS DESCRIBED IN THIS FORM.The date you sign this document to enroll in this study, that is, todays date, MUST fall between the dates indicated on the approval stamp affixed to the bottom of each page. These dates indicate that this form is valid when you enroll in the study but do not reflect how long you may participate in the study. 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