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Bioengineering

BIOE 4710 Biomechanics of Soft and Hard Tissues

Designation: ÌýÌý Elective
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Description: ÌýÌý Composite and hierarchial models of bones; models of bone remodeling. Soft tissue models; linear and nonlinear viscoelasticity, Fung's quasilinear viscoelastic theory. Biphasic and triphasic models and mechano-ionic interactions.
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Prerequisite: ÌýÌý BIOE 3110
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Textbook: ÌýÌý None
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Objectives: ÌýÌý To understand the molecular level characteristics of extracellular matrices that form musculoskeletal tissues such as tendons, ligaments, cartilage, muscle and bone. 
To understand the structural hierarchial organization and physiology of musculoskeletal tissues. 
To understand the biological and physiological factors that render these tissues the unique mechanical properties they have. 
To understand the concepts such as stress, strain, stress-strain relationships, viscoelasticity and how these concepts apply to musculoskeletal tissues. 
To understand how the mechanical function of these tissues alter with age, disease and trauma.
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Topics: ÌýÌý ³§³Ù°ù±ð²õ²õ-³§³Ù°ù²¹¾±²ÔÌý
Anisotropy/Composite Mechanics 
Linear Viscoelasticity 
Proteins of the Extracellular Matrix 
Physiology and Mechanics of Tendons/Ligaments 
Physiology and Mechanics of Bone 
Physiology and Mechanics of Muscle 
Physiology and Mechanics of Cartilage
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Schedule: ÌýÌý 2 - 1 hour and 15 minute lectures per week
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Contribution: ÌýÌý Engineering topics
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Outcomes: ÌýÌý
(a) ÌýÌý An ability to apply knowledge of mathematics, science, and engineering
(e) ÌýÌý An ability to identify, formulate, and solve engineering problems
(8a) ÌýÌý An understanding of biology and physiology
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Prepared by: ÌýÌý Scott Molitor (scott.molitor@utoledo.edu) and Tammy Phares (tamara.phares@utoledo.edu).
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